Rapid expansion of anatomical no-reflow during reperfusion in the rabbit
نویسندگان
چکیده
منابع مشابه
Microvascular reperfusion injury: rapid expansion of anatomic no reflow during reperfusion in the rabbit.
The aim was to define the degree and time course of reperfusion-related expansion of no reflow. In five groups of anesthetized, open-chest rabbits (30-min coronary occlusion and different durations of reperfusion), anatomic no reflow was determined by injection of thioflavin S at the end of reperfusion and compared with regional myocardial blood flow (RMBF; radioactive microspheres) and infarct...
متن کاملNo-reflow phenomenon persists long-term after ischemia/reperfusion in the rat and predicts infarct expansion.
BACKGROUND No-reflow after reperfusion therapy for myocardial infarction is a strong predictor of clinical outcome. But its fate on a long-term basis and potential significance for infarct healing are not yet known. METHODS AND RESULTS Twenty-nine female Fisher rats were subjected to 60 minutes of coronary occlusion followed by reperfusion. At 4 weeks, 15 survivors were euthanized after measu...
متن کاملthe effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
REPERFUSION The effect of streptokinase on intramyocardial hemorrhage , infarct size , and the no - reflow phenomenon during coronary reperfusion
The purpose of this study was to determine whether streptokinase (1) exacerbates intramyocardial hemorrhage during coronary reperfusion, (2) has any intrinsic effect on myocardial infarct size other than its ability to lyse proximal thrombi in coronary arteries, and (3) can abolish the no-reflow phenomenon. Anesthetized open-chest dogs underwent coronary occlusion for 3 hr followed by 3 hr of r...
متن کاملNo - Reflow
A. DEFINITION. The no-reflow phenomenon was originally observed in experimental models of acute myocardial infarction (MI) and was described as a failure to restore normal myocardial blood flow despite removal of the coronary obstruction. Since that time, no-reflow has been shown to complicate thrombolytic therapy and percutaneous revascularization with PTCA and other devices. Defined angiograp...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2002
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(02)81459-0